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DeCS
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Descriptor English:
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Discoidin Domain
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Descriptor Spanish:
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Dominio Discoidina
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Descriptor Portuguese:
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Domínio Discoidina
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Synonyms English:
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Discoidin Domains
Domain, Discoidin
Domains, Discoidin
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Tree Number:
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G02.111.570.820.709.275.750.219
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Definition English:
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A protein domain originally identified in DISCOIDINS. It occurs in a variety of unrelated proteins in multicellular organisms, where it recognizes different ligands with distinct biological functions. Structurally, it consists of two antiparallel beta sheets that form a "jellyroll" configuration stabilized by two intramolecular disulfide bonds. Sequence differences within this module determine ligand specificity; in DISCOIDIN DOMAIN RECEPTORS, it binds to FIBRILLAR COLLAGENS and NON-FIBRILLAR COLLAGENS. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56738
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Unique Identifier:
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D000070822
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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